Essentials of Cerebellum and Cerebellar Disorders - A Primer For Graduate Students

od Springer International Publishing
Stan: Nowy
339,52 zł
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Springer International Publishing Essentials of Cerebellum and Cerebellar Disorders - A Primer For Graduate Students
Springer International Publishing - Essentials of Cerebellum and Cerebellar Disorders - A Primer For Graduate Students

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339,52 zł zawiera VAT
Dostępnych sztuk: 1 Dostępnych tylko 1 sztuk Dostępnych ponad 10 sztuk
Dostawa: między środa, 13 lipca 2022 a piątek, 15 lipca 2022
Sprzedaż i wysyłka: Dodax


Essentials of the Cerebellum and Cerebellar Disorders is the first book of its kind written specifically for graduate students and clinicians. It is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. This monograph makes this large and expanding body of knowledge readily accessible to trainees and clinicians alike. The editors are world leaders in the field, and the chapters are authored by an international panel of experts drawn from ataxia clinics and cerebellar laboratories throughout North America, Europe and Asia. Essentials provides a solid grounding in the field of cerebellar research and ataxiology from cerebellar circuity to clinical practice, and it serves as a springboard to a deeper appreciation of both the principles and the complexities of cerebellar neurobiology. Clinicians are expected to have a deep appreciation of cerebellar disorders, not only in specialized ataxia clinics but also in adult and pediatric neurology, neurosurgery, psychiatry and neuropsychology practices, and in outpatient and inpatient rehabilitation settings. This book is an indispensable resource for students and practitioners navigating the evolving field of cerebellar motor and cognitive neurology. It also links to the more expansive Handbook for those who need to explore the topics in this monograph in greater depth.

Dalsza informacja

Adnotacja do ilustracji:
X, 656 p. 112 illus., 61 illus. in color.
Spis treści:
1. INTRODUCTION            2. BRIEF HISTORICAL NOTE          2.1.A brief history of the cerebellum2.2. The Contributions of Gordon Holmes and Olof Larsell                              3. ANATOMY AND HISTOLOGY OF THE CEREBELLUM       3.1 Gross anatomy of the cerebellum3.2 Vascular supply and territories of the cerebellum3.3 The olivocerebellar tract3.4 Pre-cerebellar nuclei3.5 Vestibular nuclei and their cerebellar connections 3.6 Spinocerebellar and cerebellospinal pathways3.7 Visual circuits3.8 Connectional anatomy of the cerebrocerebellar system         3.9 Cerebello-cerebral feedback projections  4. EMBRYOLOGY AND DEVELOPMENT OF THE CEREBELLUM 4.1 Cerebellar neurogenesis4.2 Zones and stripes4.3 Specification of cerebellar neurons4.4 Cerebellar nuclei development4.5 Development of glutamatergic and GABAergic synapses4.6 Synaptogenesis and synapse elimination in developing cerebellum4.7 Cerebellar epigenetics: Transcription of microRNAs in Purkinje cells  5. CEREBELLAR CIRCUITS: BIOCHEMISTRY, NEUROTRANSMITTERS AND NEUROMODULATION 5.1. granule cells and parallel fibers5.2. Purkinje neurons5.3. Stellate cells5.4. Basket cells5.5. Golgi neurons5.6. Lugaro cells5.7. Unipolar brush cells5.8. Glial cells5.9. GABA pathways and receptors5.10. Glutamatergic pathways and receptors5.11. Norepinephrine<5.12. Serotonin5.13. Nitric oxide5.14. Cannabinoids5.15. Purinergic signaling5.16. Neuropeptides5.17. Neurosteroids5.18. Cerebellar networks5.19. Distributed Plasticity 6. BASIC PHYSIOLOGY   6.1. Oscillation in the Inferior Olive neurons: Functional Implication6.2. Simple spikes and complex spikes6.3. Rebound Depolarization and Potentiation6.4. Cerebellar Nuclei6.5. Plasticity of cerebellum6.6. Physiology of Olivo-Cerebellar Loops6.7. Long-term depression at parallel fiber-Purkinje cell synapses6.8. Regulation of Calcium in the Cerebellum 7. NEUROIMAGING OF THE CEREBELLUM 7.1.Cerebellar closed loops7.2.MRI aspects7.3.SPECT and PET7.4.Spectroscopy7.5.Functional topography 8.FUNCTIONAL PROPERTIES OF THE CEREBELLUM 8.1.Cerebrocerebellar networks8.2.Clinical functional topography in cognition 8.3. Sequencing8.4. Speech and language  9.CELLULAR AND ANIMAL MODELS OF CEREBELLAR DISORDERS 9.1 The zebrafish cerebellum9.2 The teleost fish9.3 Lurcher mouse9.4 The tottering mouse9.5 The rolling Nagoya mouse9.6 The ataxic Syrian hamster9.7 Lesions of the cerebellum9.8 Staggerer mouse 10.HUMAN CEREBELLAR SYMPTOMS: FROM MOVEMENT TO COGNITION 10.1.Oculomotor disorders10.2.Speech deficits10.3.Deficits of limb movements10.4.Lesion-symptom mapping10.5.The cerebellar cognitive affective syndrome10.6.Clinical scales of ataxias 11.HUMAN CEREBELLAR DISORDERS: FROM PRENATAL PERIOD TO ELDERLY 11.1.Differential diagnosis based on age11.2.Pediatric ataxias – Overview11.3.Autism spectrum disorders11.4.Autosomal recessive ataxias11.5.X-linked ataxias11.6.Imaging of cerebellar malformations11.7.Cerebellar stroke11.8.Immune diseases11.9.Paraneoplastic ataxias11.10.Essential tremor11.11.Toxic agents11.12. Endocrine disorders 12.THERAPIES OF CEREBELLAR ATAXIAS 12.1.Drugs in selected ataxias12.2.Cerebellostimulation12.3.RehabilitationINDEX    
Gruol, Donna L.;Gruol
Koibuchi, Noriyuki;Koibuchi
Manto, Mario;Manto
Molinari, Marco;Molinari
Schmahmann, Jeremy D.;Schmahmann
Shen, Ying;Shen
Easy to read and short chapters

Synthesis of the major advancements in cerebellum physiology and pathology

Strong international panel of editors

Translational: from bench to bedsite

Covers the most common cerebellar disorders encountered in the clinic

Miękka oprawa
Springer International Publishing
International panel of editors: the 6 editors have a strong experience in research and/or in the clinic. They all devote most of their time to cerebellar research and have regular teaching duties for several of them. Through their networks, their students and the attendance to international conferences, they will contribute to a fast dissemination of the book.
International panel of authors: the book will gather an international panel of scientists who are key-players in the field. They are located in USA, in Europe and in Asia. Many of them have contributed to the Handbook and we also aim to attract novel authors or young talented scientists. The authors will come from the best clinical centers, universities or research centers in the world.
Softcover reprint of the original 1st ed. 2016
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339,52 zł
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