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The biopharmaceutical industry has been a major driver of technological change in health care, producing unprecedented benefits for patients, cost challenges for payers, and profits for shareholders. As consumers and companies benefit from access to new drugs, policymakers around the globe seek mechanisms to control prices and expenditures commensurate with value. More recently the 1990s productivity boom of new products has turned into a productivity bust, with
fewer and more modest innovations, and flat or declining revenues for innovative firms as generics replace their former blockbuster products.

This timely volume examines the economics of the biopharmaceutical industry, with 18 chapters by leading academic health economists. Part one examines the economics of biopharmaceutical innovation including determinants of the costs and returns to new drug development; how capital markets finance R&D and how costs of financing the biopharmaceutical industry compare to financing costs for other industries; the effects of safety and efficacy regulation by the Food and Drug Administration
(FDA) and of price and reimbursement regulation on incentives for innovation; and the role of patents and regulatory exclusivities. Part two examines the market for biopharmaceuticals with chapters on prices and reimbursement in the US, the EU, and other industrialized countries, and in developing
countries. It looks at the optimal design of insurance for drugs and the effects of cost sharing on spending and on health outcomes; how to measure the value of pharmaceuticals using pharmacoeconomics, including theory, practical challenges, and policy issues; how to measure pharmaceutical price growth over time and recent evidence; empirical evidence on the value of pharmaceuticals in terms of health outcomes; promotion of pharmaceuticals to physicians and consumers; the economics of vaccines;
and a review of the evidence on effects of mergers, acquisitions and alliances.

Each chapter summarizes the latest insights from theory and recent empirical evidence, and outlines important unanswered questions and areas for future research. Based on solid economics, it is nevertheless written in terms accessible to the general reader. The book is thus recommended reading for academic economists and non-economists, and for those in industry and policy who wish to understand the economics of this fascinating industry.


I was certainly impressed by the breadth of the book... the various authors do a good job in developing the concepts in a readily understood fashion. John R. Cook, Journal of Biopharmaceutical Statistics


This volume comprises 18 chapters by leading academics on the economics of the biopharmaceutical industry. Part one examines economic determinants of biopharmaceutical R&D including financing, regulation, and patents. Part two addresses major issues in pharmaceutical markets including pricing, price regulation, and promotion; insurance coverage and effects of patient cost-sharing; the health value of pharmaceuticals; and the endemic use of mergers, acquisitions,
and alliances.


Redaktor Patricia M. Danzon

Redaktor Sean Nicholson

Szczegóły produktu


GTIN 9780199742998

Data premiery rynkowej 28.06.2012

Język Angielski

Liczba stron 624

Product type Książka

Wielkość 255 x 180 x 36  mm

Ciężar produktu 1331 g

The Oxford Handbook of the Economics of the Biopharmaceutical Industry

Patricia M. Danzon

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